KEY
CLINICAL CHEMISTRY 3 2012-2013 PRELIM
EXAMS
I.
Identification: (1 pt. each)
1.
_____PROTEIN___________________________________ The chemical
nature of enzymes.
2.
PEPTIDE,
STEROIDS, EICOSANOIDS, AMINE_____The chemical nature of
hormones.
3.
_____CORTISOL
BINDING GLOBULIN____________
The major binding protein of cortisol.
4.
_____T3, OR
TRIIDOTHYRONINE________________ The more potent thyroid hormone.
5.
______RT3U OR
THBR____________________________ The
test that measures the available binding sites of TBG.
6.
______EMIT ______________________________________ The test that does not need the separation of
the free T4 from the bound T4.
7.
______SOLID
PHASE ANTIBODY___________________ This
test makes use of two antibody phases.
8.
______ULTRASOUND______________________________ This test makes
use of high frequency sound waves to determine the organ dysfunction.
9.
______ANS_______________________________________ This is the
reagent that separates T4 from the bound.
10. ______SEE NOTES__________________________________ Give one
precaution for Thyroid hormone determination.
TEST II. MULTIPLE CHOICE ANSWERS
1. D
|
11. D
|
21. D
|
31. C
|
41. K
|
51. Q, R
|
2. D
|
12. D
|
22. BONUS
|
32. D
|
42. T
|
52. D
|
3. C
|
13. C
|
23. D
|
33. C
|
43. F
|
53. D
|
4. D
|
14. B
|
24. B
|
34. D
|
44. C
|
54. D
|
5. C
|
15. A
|
25. C
|
35. D
|
45. G
|
55. D
|
6. A
|
16. B
|
26. A
|
36. B
|
46. D
|
|
7. C
|
17. B
|
27. B
|
37. D
|
47. F, P
|
|
8. D
|
18. B
|
28. C
|
38. BONUS
|
48. L
|
|
9. D
|
19. C
|
29. D
|
39. B
|
49. I
|
|
10. B
|
20. B
|
30.B
|
40. A
|
50. E, M
|
|
TEST III. MATCHING TYPE
1.
A,
B 6. A
2.
B 7. A
3.
A,
B 8. B
4.
A 9. B
5.
A 10. A
TEST IV CASE
ANALYSIS:
1.
WHAT FURTHER
TESTS WOULD YOU RECOMMEND? DEFEND YOUR ANSWER.
FT3
FT4
TSH
THBR
CORTISOL
THE SYMPTOMS OF THE PATIENT MIMIC THAT
OF A PERSON WITH THYROID AND ADRENAL DYSFUNCTION. SINCE THE LABORATORY RESULTS
ARE ALL NORMAL, EXCEPT FOR HEMOGLOBIN, WHICH IS SLIGHTLY BELOW NORMAL VALUES
FOR MALE, THE NEXT OPTION IS TO CONSIDER METABOLIC DISORDERS.
THE SLIGHTLY LOW HEMOGLOBIN VALUES OF THE
PATIENT IS NOT CRITICAL BECAUSE THE BLOOD MORPHOLOGY SHOWED NORMAL CELLS,
HENCE, ITS SLIGHTLY LOW VALUE COULD BE
BECAUSE OF LESS SERIOUS CAUSES LIKE MALNUTRITION, AND SIMILAR CASES.
2.
WHAT WOULD BE
THE MOST LIKELY DIAGNOSIS? DEFEND YOUR ANSWER.
THE MOST LIKELY DIAGNOSIS WOULD BE
HYPERTHYROIDISM AND HYPERADRENALISM, MOST LIKELY, GRAVE’S DISEASE.
THE OVERALL DATA OF THE PATIENT SHOULD
BE COLLATED FIRST (HISTORY, PHYSICAL SYMPTOMS, LABORATORY RESULTS, AND OTHER
DIAGNOSTICS TESTS) BEFORE COMING TO A CONCLUSION.
FOR THE RIA METHOD REFER TO NOTES.
FOR THE TRANSCRIPTION- PLS RESEARCH
